2022-present

• FoxP1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to regulate neural progenitor cell maintenance
  Buth JE, Dyevich CE, Rubin A, Wang C, Gao L, Marks T, Harrison MRM, Kong JH, Ross ME, Novitch BG, Pearson CA.
  Accepted at EMBO Reports.

• Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
  Liu X, Yam PT, Schlienger S, Cai E, Zhang J, Chen W, Gutierrez OT, Amilburu VJ, Ramamurthy V, Ting AY, Branon TC, Cayouette M, Gen R, Marks T, Kong JH, Charron F, Ge X. bioRxiv 2022.10.10.511655; doi: https://doi.org/10.1101/2022.10.10.511655 *March 4th, 2024 — Accepted at Nature Communications

• Creating accessibility in academic negotiations.
  *Kong JH, *Vasquez CG, Agrawal S, Malaney P, Mikedis MM, Moffitt AB, von Diezmann L, Termini CM. Trends in Biochemical Sciences. 2022 Dec 8:S0968-0004(22)00287-0. doi: 10.1016/j.tibs.2022.10.004. .
  PubMed PMID: 36504139.

2016-2021

• Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength.
  Kong JH, Young CB, Pusapati GV, Espinoza FH, Patel CB, Beckert F, Ho S, Patel BB, Gabriel GC, Aravind L, Bazan JF, Gunn TM, Lo CW, Rohatgi R. Development. 2021 Oct 1; 148(19):dev199867.
  PubMed PMID: 34486668. PubMed Central PMCID: PMC8513608.

• Ten simple rules for writing compelling recommendation letters.
  Kong JH, Steele LJ, Botham CM. PLoS Computational Biology. 2021 Feb 25; 17(2): e1008656.
  PubMed PMID: 33630854. PubMed Central PMCID: PMC7906297.

• A membrane-tethered ubiquitination pathway regulates Hedgehog signaling and heart development.
  *Kong JH, *Young CB, *Pusapati GV, Patel CB, Ho S, Krishnan A, Lin JI, Devine W, Moreau de Bellaing A, Athni TS, Aravind L, Gunn TM, Lo CW, Rohatgi R. Developmental Cell. 2020 Nov 23;55(4).
  PubMed PMID: 32966817. PubMed Central PMCID: PMC7686252.
  

• Suffering from COVD-19 anxiety? Here’s what you can do.
  Kong JH, Chan S. Science Careers. 2020 April 23. DOI: 10.1126/science.caredit.abc4052.

• Cholesterol accessibility at the ciliary membrane controls hedgehog signaling. *Kinnebrew M, *Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R. eLife. 2019 Oct 30;8.
  PubMed PMID: 31657721. PubMed Central PMCID: PMC6850779.

• Biochemical mechanisms of vertebrate hedgehog signaling (Review).
  Kong JH, Siebold C, Rohatgi R. Development. 2019 May 15;146(10).
  PubMed PMID: 31092502. PubMed Central PMCID: PMC6550017. 

• New perspectives on the mechanisms establishing the dorsal-ventral axis of the spinal cord (Review).
  Andrews MG, Kong J, Novitch BG, Butler SJ. Current Topics in Developmental Biology. 2019 132:417-450.
  PubMed PMID: 30797516. PubMed Central PMCID: PMC5811045.

• Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
  *Sagner A, *Gaber ZB, *Delile J, Kong JH, Rousso DL, Pearson CA, Weicksel SE, Melchionda M, Mousavy Gharavy SN, Briscoe J, Novitch BG. PLoS Biology. 2018 Feb;16(2):e2003127.
  PubMed PMID: 29389974. PubMed Central PMCID: PMC5811045.

• G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
  *Pusapati GV, *Kong JH, Patel BB, Gouti M, Sagner A, Sircar R, Luchetti G, Ingham PW, Briscoe J, Rohatgi R. Science Signaling. 2018 Feb 6;11(516).
  PubMed PMID: 29438014. PubMed Central PMCID: PMC5828112.

• Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.
  *Pusapati GV, *Kong JH, *Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R. Developmental Cell. 2018 Jan 8;44(1):113-129.e8.
  PubMed PMID: 29290584. PubMed Central PMCID: PMC5792066.

• Netrin1 produced by neural progenitors, not floor plate cells, is required for axon guidance in the spinal cord.
  Varadarajan SG, Kong JH, Phan KD, Kao TJ, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ. Neuron. 2017 May 17;94(4):790-799.e3.
  PubMed PMID: 28434801. PubMed Central PMCID: PMC5576449.

• Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling. *Luchetti G, *Sircar R, Kong JH, Nachtergaele S, Sagner A, Byrne EF, Covey DF, Siebold C, Rohatgi R. eLife. 2016 Oct 5;5:e20304.
  PubMed PMID: 27705744. PubMed Central PMCID: PMC5123864.

2012-2015

• Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling.
  *Kong JH, *Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG. Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Developmental Cell. 2015 May 26;33(4):373-87.
  PubMed PMID: 25936505. PubMed Central PMCID: PMC4449290.

• Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R. Cell Reports. 2014 Jan 16;6(1):168-181.
  PubMed PMID: 24373970. PubMed Central PMCID: PMC3915062.

• Retinoid acid specifies neuronal identity through graded expression of Ascl1.
  Jacob J, Kong J, Moore S, Milton C, Sasai N, Gonzalez-Quevedo R, Terriente J, Imayoshi I, Kageyama R, Wilkinson DG, Novitch BG, Briscoe J. Current Biology. 2013 Mar 4;23(5):412-8.
  PubMed PMID: 23416099. PubMed Central PMCID: PMC3659286.

• Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.
  Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL. PNAS. 2012 May 15;109(20):7882-7. PubMed PMID: 22543161. PubMed Central PMCID: PMC3356608.